Quantitative analysis of first-pass contrast-enhanced myocardial perfusion MRI using a patlak plot method and blood saturation correction
نویسندگان
چکیده
منابع مشابه
Quantitative myocardial perfusion analysis with a dual-bolus contrast-enhanced first-pass MRI technique in humans.
PURPOSE To compare fully quantitative and semiquantitative analysis of rest and stress myocardial blood flow (MBF) and myocardial perfusion reserve (MPR) using a dual-bolus first-pass perfusion MRI method in humans. MATERIALS AND METHODS Rest and dipyridamole stress perfusion imaging was performed on 10 healthy humans by administering gadolinium contrast using a dual-bolus protocol. Ventricul...
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First-pass contrast-enhanced myocardial perfusion MRI in rodents has so far not been possible due to the temporal and spatial resolution requirements. We developed a new first-pass perfusion MR method for rodent imaging on a clinical 3.0-T scanner (Philips Healthcare, Best, The Netherlands) that employed 10-fold k-space and time domain undersampling with constrained image reconstruction, using ...
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PURPOSE Perfusion analysis from first-pass contrast enhancement kinetics requires modeling tissue contrast exchange. This study presents a new approach for numerical implementation of the tissue homogeneity model, incorporating flexible distance steps along the capillary (NTHf). METHODS The proposed NTHf model considers contrast exchange in fluid packets flowing along the capillary, incorpora...
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PURPOSE To study the nonlinearity of myocardial signal intensity and gadolinium contrast concentration during first-pass perfusion MRI, and to compare quantitative perfusion estimates using nonlinear myocardial signal intensity correction. MATERIALS AND METHODS The nonlinearity of signal intensity and contrast concentration was simulated by magnetization modeling and evaluated in phantom meas...
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Introduction: First-pass myocardial perfusion imaging (MPI) is now an established tool for the assessment of ischemic heart disease, and the most widely used protocols involve 2D multi-slice acquisition. Three-dimensional (3D) MPI is potentially advantageous due to its contiguous spatial coverage and high SNR [1], and has been recently shown to be more accurate than 2D multi-slice techniques in...
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ژورنال
عنوان ژورنال: Magnetic Resonance in Medicine
سال: 2009
ISSN: 0740-3194
DOI: 10.1002/mrm.22018